I'd have to buy a road bike, but possibly. Nothing like the old man crew whopping up on my 20'something ass.
I think I tried Gambrill once. (I get that and the Frederick watershed confused) either way what I road was really rocky and technical. Far above my expertise.
I didn't mind Seneca for those same reasons, it was a nice comfortable ride. I plan to make it down to Schaeffer, but I don't know if it'll be this year or next. I've heard nothing but good things about it